PT Mixing Studies
| Sunquest Code: | PT1T2 | ||
| Epic Code: | LAB3698 | Epic Name: | PT Mixing Studies |
| Synonyms: | INR Mixing Study | ||
| Methodology: | An INR assay of patient/normal plasma mixture at 1:2 dilution | ||
| Turnaround Time: | Performed and reported 24 hours per day. | ||
| Special Instructions: | INR must be elevated for age group for the PT mixing study to be performed. | ||
| Associated Links: | Specimen Collection and Processing for Coagulation Specimens |
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Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2.7 mL (in 3 mL tube) - filled to fill line on the tube |
| Minimum\Peds Volume: | 1.8 mL (in 2 mL tube) - filled to fill line on the tube |
| Container: | Blue Na Citrate, 3.2% - fill to fill line on tube |
| Collection Instructions: | If the patient's hematocrit is >55%, contact laboratory to obtain a special tube.
If using a butterfly needle, a waste tube must be collected before the blue top. |
| After Care: | If the patient has a coagulation abnormality, apply direct pressure to the puncture site for 10 minutes; apply a pressure dressing. Instruct the patient to leave the bandage on for 12 hours. |
| Causes for Rejection: | Underfilled tubes, overfilled tubes, clotted specimens, specimens collected in 3.8% buffered citrate, specimen greater than 8 hours old or not processed appropriately within 8 hours after collection, or specimens stored in the refrigerator. |
Processing and Shipping
| Specimen Processing: | Send whole blood or platelet poor plasma. See Associated Link for additional processing instructions. |
| Shipping Instructions: | Ship whole blood specimens at room temperature. Whole blood specimens must arrive within 8 hours. If greater than 8 hours is required for transport, follow specimen processing instructions and ship frozen plasma on dry ice. |
| Test Performed at or Referral Lab | Coagulation (UMMC-East Bank) |
Interpretive
| Use: | To test for presence of an inhibitor. |
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