Soluble Transferrin Receptor


Sunquest Code:STR  
Epic Code:LAB3753Epic Name:Soluble Transferrin Receptor
Synonyms:Transferrin Receptor Level
Methodology:Immunoturbidimetric
Turnaround Time:Specimens are sent to the reference laboratory Mon-Sat; results are reported within 24 hours.


Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:0.8 mL
Container:Red or gold (gel) (Green (lithium heparin, no gel), Green (lithium heparin, gel), Green (sodium heparin, no gel), Purple (EDTA), Red (no gel))
Causes for Rejection:Severely hemolyzed, lipemic, icteric.


Processing and Shipping

Specimen Processing:Centrifuge and aliquot 1 mL, 0.3 mL minimum ASAP. Samples are stable refrigerated for 7 days.
Shipping Instructions:Ship at refrigerated temperature.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:70283 (STR)


Interpretive

Reference Range:
 
Male, 18 & older 2.2-5.0 mg/L
Female, 18 & older 1.9-4.4 mg/L
People of African descent and those residing at 5200 feet (1600 meters) above sea level were found to have a 6% higher normal value. These differences were additive. No reference values have been established for pregnant females, subjects under 18 years of age, and recent or frequent blood donors.
Use:Serum soluble transferrin receptor increases in iron deficiency and is usually unaffected by chronic disease states. In general, to increase sensitivity and specificity, the measurement of serum soluble transferring receptor should be performed in combination with other tests of iron status, including ferritin, tIBC and serum iron. Refer to table below:
  Test for
changes in:		 Iron
Deficiency
Anemia		 Anemia of
Chronic
Disease 		Iron Deficiency
& Anemia of
Chronic Disease
Ferritin Iron
Stores		 Low High Normal
or High
TIBC Iron
Status		 High Low Normal
or High
Serum Iron Iron
Status		 Low Low Low
sTfR Iron
Status		 High Normal High
   


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