Inflammatory Bowel Disease Differentiation Panel


Abbrev Code:ARMISC   
Order Code:LAB5867Order Name:Inflammatory Bowel Disease
Synonyms:Irritable Bowel Disease; IBDS; IBDSGI
Methodology:Enzyme-linked immunosorbent assay; indirect fluorescent antibody
CPT Codes: 86671 x2, 86671 x2, 86036 x1, 86036 x1, 86037 x1, 86037 x1
Turnaround Time:Specimens are sent to the reference laboratory Mon-Sat; results are reported within 1-4 days,


Collection Instructions

Specimen:Blood
Optimal Volume:3 mL
Minimum\Peds Volume:1.4 mL
Container:Red or gold (gel)
Causes for Rejection:Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.


Processing and Shipping

Specimen Processing:Within 2 hours of collection, centrifuge and aliquot 1 mL, 0.6 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Stability:After separation from cells: 48 hours at room temperature; 2 weeks refrigerated; 1 year frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:3003748


Interpretive

Reference Range:

S. cerevisiae Antibody, IgG

 

20.0 Units or less

Negative

20.1-24.9 Units

Equivocal

25.0 Units or greater

Positive

 

S. cerevisiae Antibody, IgA

 

20.0 Units or less

Negative

20.1-24.9 Units

Equivocal

25.0 Units or greater

Positive

 

Anti-Neutrophil Cytoplasmic  Antibody, IgG

Less than1:20: Not significant

 

Use:This test may be a useful tool for distinguishing ulcerative colitis (UC) from Crohn Disease (CS in patients with suspected inflammatory bowel disease. If the ANCA screen detects antibodies at a 1:20 dilution or greater, then a titer to end point will be added. Additional charges apply. ANCA IFA is simultaneously tested on ethanol- and formalin-fixed slides to allow differentiation of C- and P-ANCA patterns.


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