Lysozyme
| Abbrev Code: | LYSO | ||
| Order Code: | LAB4190 | Order Name: | Lysozyme |
| Methodology: | Enzyme-linked immunosorbent assay | ||
| CPT Codes: | 85549 x1 | ||
| Turnaround Time: | Specimens are sent to reference laboratory Mon-Sat; results are reported in 1-5 days. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2 mL blood |
| Minimum\Peds Volume: | 1 mL blood |
| Container: | Red or gold (gel) Alternate Containers: Red (no gel) |
| Causes for Rejection: | Hemolyzed, lipemic, icteric or contaminated specimens. Room temperature specimens. |
Processing and Shipping
| Specimen Processing: | Separate serum from cells within 2 hours of collection. Aliquot 1 mL, 0.4 mL minimum, serum. Store in refrigerator. |
| Shipping Instructions: | Ship at refrigerated temperature. |
| Stability: | Room temperature unacceptable; 5 days refrigerated, 1 month frozen. |
| Test Performed at or Referral Lab | Lab Sendouts (ARUP) |
| Referral Lab number: | 2012039 |
Interpretive
| Reference Range: | Less than or equal to 2.75 ug/mL |
| Use: | Serum lysozyme levels may be elevated in acute myelomonocytic leukemia (FAB-M4), chronic myelomonocytic leukemia (CMML), and chronic myelocytic leukemia (CML). Increased serum lysozyme activity is present in tuberculosis, sarcoidosis, megaloblastic anemias, acute bacterial infections, ulcerative colitis, regional enteritis,and Crohn disease. Elevated levels of serum lysozyme occur during severe renal insufficiency, renal transplant rejection, urinary tract infections, pyelonephritis, glomerulonephritis and nephrosis. |
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