Iron and Iron Binding Capacity (IBC)
Abbrev Code: | FEBC | ||
Order Code: | LAB829 | Order Name: | Iron and Iron Binding Capacity |
Order Instructions: | Test code generates FE, FEB, ISI | ||
Synonyms: | LAB3467; Iron Saturation; FEBC; TIBC | ||
Methodology: | Roche:
Vista: Biochromatic end point |
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CPT Codes: | 83550 x1, 83550 x1, 83540 x1, 83540 x1 | ||
Test Includes: | Iron, % saturation, total iron binding capacity | ||
Turnaround Time: | Performed and reported daily. | ||
Special Instructions: | Falsely elevated iron levels will result if the patient has received Imferon within the past two months. | ||
Associated Links: |
Collection Instructions
Specimen: | Blood |
Optimal Volume: | 2.5 mL |
Minimum\Peds Volume: | 0.6 mL |
Collection Instructions: | Chemistry Tests Containers Chart
Collect sample before patient is given therapeutic iron or a blood transfusion. Blood transfusion can transiently (<24 h) increase serum iron concentration and transferrin saturation (but not total iron binding capacity), particularly if the blood has been stored for a longer period (Blood 2011 Dec 15; 118(25):6675-82; Arch Pathol Lab Med 1993 Jun; 117(6):(622-4).Therefore, if a patient has received blood, delay testing for 24 hours to avoid false elevation of iron or transferrin saturation. Calculation for Transferrin Saturation: (serum iron/TIBC) x 100. Li heparin in plasma values are aproximately 6% lower than serum values. |
Causes for Rejection: | Hemolysis |
Processing and Shipping
Specimen Processing: | Centrifuge within 4 hours and aliquot 1.25 mL, 0.2 mL minimum. Store in refrigerator.
If samples contain precipitate, centrifuge before testing. |
Shipping Instructions: | Ship at refrigerated temperature. |
Stability: | Roche: 7 days at room temperature; 3 weeks refrigerated; 2 years frozen.
Vista: 7 days refrigerated; 6 months frozen. |
Test Performed at or Referral Lab | Chemistry (CSC Maple Grove, Roche-CSC Mpls, Roche-Grand Itasca, Roche-Lakes, Roche-Northland, Roche-Range, Roche-Ridges, Roche-Southdale, Roche-St. John's, Roche-UMMC East, Roche-UMMC West) |
Interpretive
Reference Range: | Roche:
Vista:
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Use: | Increased iron saturation occurs with hemochromatosis, lead poisoning, thalassemia. Decreased iron saturation occurs with iron deficiency. May be normal with anemia or chronic disease. |
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