CRP Cardiac Risk
| Sunquest Code: | CRPHS | ||
| Epic Code: | LAB4516 | Epic Name: | CRP Cardiac Risk |
| Synonyms: | C Reactive Protein High Sensitivity | ||
| Methodology: | Nephelometry
Grand Itasca: Latex immunoturbidity St Joseph: Immunoturbidmetric |
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| Turnaround Time: | Performed and reported 24 hours/day. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2.5 mL |
| Minimum\Peds Volume: | 0.6 mL |
| Container: | Green (lithium heparin, gel), Grand Itasca - Green (lithium heparin, gel), St Joes - Green (lithium heparin, no gel) (Grand Itasca - Red (no gel), Red (no gel), Red or gold (gel), St. Joes - Red no gel) |
| Causes for Rejection: | Samples not separated from cells within 2 hours of collection. |
| Contraindications: | Do not order this test for indicator of inflammation; order C-Reactive Protein, Inflammation. |
Processing and Shipping
| Specimen Processing: | Within 2 hours centrifuge and aliquot 1.25 mL, 0.2 mL minimum. Store in refrigerator. |
| Shipping Instructions: | Ship at refrigerated temperature. |
| Stability: | 7 days refrigerated; up to 8 months frozen at -20°C. |
| Test Performed at or Referral Lab | Chemistry (UMMC-East Bank, Grand Itasca, St. Joseph's) |
Interpretive
| Reference Range: |
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| Use: | C-Reactive Protein, Cardiac Risk is often referred to as high-sensitivity CRP (hs-CRP). This test measures the much lower amounts of CRP in the blood of normal individuals who lack overt inflammatory conditions. It is used to assess cardiac risk. Adding measurement of hs-CRP to results from a fasting lipid panel further improves the identification of patients at risk for cardiovascular events. Individuals with comparable LDL-and HDL-cholesterols who have hs-CRP in the higher part of the normal range (e.g. greater than 3.0 mg/L) are at higher risk for developing atherosclerotic disease events than those with hs-CRP results in the lower part of the reference range (e.g. less than 1.0 mg/L). When using the assay for risk assessment, patients with persistently unexplained, marked elevation of hsCRP (>10 mg/L) after repeated testing should be evaluated for non-cardiovascular etiologies. |
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