Glutamic Acid Decarboxylase Antibody

Abbrev Code:GAD   
Order Code:LAB3488Order Name:Glutamic Acid Decarboxylase Antibody
Methodology:Enzyme-linked immunosorbent assay
CPT Codes: 86341 x1
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported in 1-3 days.

Collection Instructions

Optimal Volume:2 mL
Minimum\Peds Volume:1.2 mL
Container:Red or gold (gel)
Alternate Containers: Red (no gel)
Causes for Rejection:Plasma, grossly hemolyzed specimens

Processing and Shipping

Specimen Processing:Centrifuge and aliquot 1 mL, 0.5 mL minimum. Store in freezer.
Shipping Instructions:Ship on dry ice.
Stability:24 hours at room temperature; 1 week refrigerated; 3 months frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:2001771


Reference Range:0.0-5.0 IU/mL
A value greater than 5.0 Kronos IU/mL is considered positive for Glutamic Acid Decarboxylase Antibody.
Use:GAD antibodies are present in the majority of individuals with new-onset diabetes and in individuals in the prediabetic phase of the disease. GAD antibodies appear early in the disease process prior to clinical symptoms and can be used to produce who will develop IDDM. Because GAD antibody is present in association with islet cell destruction, it can also be utilized to differentiate IDDM from non-insulin dependent diabetes (NIDDM). The development of GAD antibody in NIDDM patients can be useful to determine which patients may later require insulin therapy.

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