Ehrlichia Chaffeensis Antibodies, IgG and IgM


Abbrev Code:ERABGM   
Order Code:LAB3453Order Name:Ehrlichia Chaffeensis Abys IGG and IGM
Synonyms:HME; Human Monocytic Ehrlichiosis; Tick-borne Diseases
Methodology:Indirect Fluorescent Antibody
CPT Codes: 86666 x2
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported in 1-5 days.
Special Instructions:Parallel testing is preferred. Label samples as acute or convalescent. Convalescent specimens must be received within 30 days from receipt of the acute specimens.
Compliance:

For tests developed and validated by ARUP (previously referred to as Compliance Statement B, C or D). This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the U.S. Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.


Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:0.8 mL
Container:Red or gold (gel)
Alternate Containers: Red (no gel)
Causes for Rejection:Lipemic, hemolytic or contaminated specimens.


Processing and Shipping

Specimen Processing:Centrifuge and aliquot 1 mL, 0.3 mL minimum. Separate serum from cells ASAP. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Stability:After separation from cells: 48 hours at room temperature; 2 weeks refrigerated; 1 month frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:51002


Interpretive

Reference Range:
Ehrlichia chaffeensis Antibody IgG by IFA
Less than 1:64 Negative. No significant level of Ehrlichia chaffeensis IgG antibody detected.
1:64-1:128 Equivocal. Questionable presence of Ehrlichia chaffeensis IgG antibody detected. Repeat testing in 10-14 days may be helpful.
Greater than or equal to 1:256 Positive. Presence of IgG antibody to Ehrlichia chaffeensis detected, suggestive of current or past infection.
 
Ehrlichia chaffeensis Antibody IgM by IFA
Less than 1:16 Negative. No significant level of Ehrlichia chaffeensis IgM antibody detected.
Greater than or equal to 1:16 Positive. Presence of IgM antibody to Ehrlichia chaffeensis detected, suggestive of current or recent infection.
 
Use:Human ehrlichiosis is a tick-borne disease caused by rickettsial-like agents. Two forms, human monocytic ehrlichiosis (HME) and human granulocytic ehrlichiosis (HGE) have been described. HME is often referred to as "spotless" or rashless Rocky Mountain spotted fever, and has been reported in various regions of the United states. The causative agent of HME has been identified as Ehrlichia chaffeensis. Infected individuals produce specific antibodies to Ehrlichia chaffeensis which can be detected by an immunofluorescent antibody (IFA) test.


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