Ribosomal P Protein Antibody, IgG


Sunquest Code:ARMISC  
Epic Code:LAB4909Epic Name:Send Outs Misc Test
Synonyms:rRNP; RNA (Ribonucleo protein) Autoantibodies
Methodology:Multiplex bead assay
Turnaround Time:Specimens are sent to the reference laboratory Mon-Sat; results are reported within 1-2 days.


Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:0.6 mL
Container:Red or gold (gel) (Red (no gel))
Causes for Rejection:Plasma or other body fluids. Bacterially contaminated or severely lipemic specimens.


Processing and Shipping

Specimen Processing:Within 2 hours of collection, centrifuge and aliquot 1 mL, 0.2 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Stability:After separation from cells: 48 hours at room temperature; 2 weeks refrigerated; 1 year frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:99249


Interpretive

Reference Range:
29 AU/mL or less Negative
30-40 AU/mL Equivocal
41 AU/mL or greater Positive
 
Use:Autoantibodies reacting with cytoplasmic ribosomes are highly specific for systemic lupus erythematosus. Ribosomal-P antibodies are found in approximately 12% of patients with systemic lupus erythematosus (SLE) and in 90% of patients with lupus psychosis; titers often increase more than five fold during and before active phases of psychosis.


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