Ribosomal P Protein Antibody, IgG
| Abbrev Code: | ARMISC | ||
| Order Code: | LAB4909 | Order Name: | Send Outs Misc Test |
| Synonyms: | rRNP; Anti-Ribosome-P Antibodies; Ribosome Antibody; Ribosomal P Antibodies | ||
| Methodology: | Multiplex bead assay | ||
| CPT Codes: | 83516 x1 | ||
| Turnaround Time: | Specimens are sent to the reference laboratory Mon-Sat; results are reported within 1-2 days. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2 mL |
| Minimum\Peds Volume: | 0.6 mL |
| Container: | Red or gold (gel) Alternate Containers: Red (no gel) |
| Causes for Rejection: | Plasma or other body fluids. Bacterially contaminated or severely lipemic specimens. |
Processing and Shipping
| Specimen Processing: | Within 2 hours of collection, centrifuge and aliquot 1 mL, 0.2 mL minimum. Store in refrigerator. |
| Shipping Instructions: | Ship at refrigerated temperature. |
| Stability: | After separation from cells: 48 hours at room temperature; 2 weeks refrigerated; 1 year frozen. |
| Test Performed at or Referral Lab | Lab Sendouts (ARUP) |
| Referral Lab number: | 99249 |
Interpretive
| Reference Range: |
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| Use: | Autoantibodies reacting with cytoplasmic ribosomes are highly specific for systemic lupus erythematosus. Ribosomal-P antibodies are found in approximately 12% of patients with systemic lupus erythematosus (SLE) and in 90% of patients with lupus psychosis; titers often increase more than five fold during and before active phases of psychosis. |
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