Cyclic Citrullinated Peptide Antibody, IgG
| Sunquest Code: | CCPIGG | ||
| Epic Code: | LAB6604 | Epic Name: | Cyclic Citrullinated Peptide IgG |
| Synonyms: | Anti-CCP; CCP Antibody | ||
| Methodology: | FEIA (by ImmunoCAP) | ||
| Turnaround Time: | Performed Mon-Fri; results are reported the same day. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 1 mL |
| Minimum\Peds Volume: | 0.6 mL |
| Container: | Red or gold (gel) [Alternate Containers: Green (lithium heparin, gel), Green (sodium heparin, no gel), Purple (EDTA), Red (no gel)] |
| Causes for Rejection: | Hemolyzed, lipemic or microbially contaminated specimens. Samples not separated from cells within 2 hours of collection. |
Processing and Shipping
| Specimen Processing: | Within 2 hours centrifuge and aliquot 0.5 mL, 0.2 mL minimum. Store in refrigerator. |
| Shipping Instructions: | Ship at refrigerated temperature. |
| Test Performed at or Referral Lab | Endocrine (UMMC-East Bank) |
Interpretive
| Reference Range: |
Approximately 70% of patients with RA are positive for CCP, while only 5% of random blood donors and disease controls are positive. The diagnostic value of antibodies to CCP in juvenile rheumatoid arthritis patients has not been determined.
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