Drug Abuse Screen, Blood with Reflex Confirmation

Abbrev Code:DS9   
Order Code:LAB1147Order Name:Drug Screen 9 Ser/Pla W/RFLX to Conf
Methodology:Qualitative enzyme linked immunosorbent assay/Quantitative gas chromatography-Mass spectrometry/Quantitative liquid chromatography-Tandem mass spectrometry
CPT Codes: 80307 x1, 80307 x1
Test Includes:Amphetamines, metamphetamine, barbiturates, benzodiazepines, buprenorphine, cannabinoids, cocaine, methadone, opiates, oxycodones, phencyclidine (PCP)
Turnaround Time:Specimens are sent to the reference laboratory Sun-Sat; results are reported within 2-3 days; confirmation 1-4 days.

This test uses a manufacturer labeled Analyte Specific Reagent (ASR) as the reagent providing the specificity of the assay. The test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Collection Instructions

Optimal Volume:8 mL
Minimum\Peds Volume:6.2 mL
Container:Red (no gel)
Alternate Containers: Green (sodium heparin, no gel), Gray (sodium fluoride + potassium oxalate), Purple (EDTA)
Collection Instructions:Cocaine and cocaethylene are more stable in fluoride-preserved plasma than serum.
Causes for Rejection:Specimens exposed to repeated freeze/thaw cycles. Collection in serum or plasma separator tubes or in blue (sodium citrate) tubes. Hemolyzed specimens.

Processing and Shipping

Specimen Processing:Centrifuge and aliquot serum or plasma within 2 hours of collection, 4 mL, 3 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Stability:After separation from cells: 1 week at room temperature; 2 weeks refrigerated; 3 years frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:0092420


Reference Range:Refer to cut off levels in the Use field.
Use:Drugs/Drug classes reported as "Positive" are automatically reflexed to mass spectrometry confirmation/quantitation. An unconfirmed positive immunoassay screen result may be useful for medical purposes, but does not meet forensic standards. The absence of expected drug(s) and/or drug metabolite(s) may indicate noncompliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, or limitations of testing. The concentration at which the screening test can detect a drug or metabolite varies within a drug class. Specimens for which drugs or drug classes are detected by the screen are automatically reflexed to a second, more specific technology (GC/MS and/or LC-MS/MS). The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.

For medical purposes only, not value for forensic use.
Drug Cutoff Level
Amphetamines 20 ng/mL
Methamphetamine 20 ng/mL
Barbiturates 50 ng/mL
Benzodiazepines 50 ng/mL
Buprenorphine 1 ng/mL
Cannabinoids 20 ng/mL
Cocaine 20 ng/mL
Methadone 25 ng/mL
Opiates 20 ng/mL
Oxycodone 20 ng/mL
Phencyclidine 10 ng/mL

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