Creatinine Clearance, Clinics Only

Sunquest Code:CRCLC  
Epic Code:LAB3898Epic Name:Creatinine Clearance AMB
Order Instructions:Enter collection volume (XXXX.), Duration (XX.X), height (XXX. in cm) and weight (XX.X in kg). Do not use semi-colons.
Synonyms:CreatClearance; CRCLC
Test Includes:Urine creatinine, raw clearance and standard clearance.
Turnaround Time:Performed and reported 24 hours/day.
Special Instructions:Blood creatinine must be collected within 24 hours of the urine collection. Record the patient's height and weight on request form.
Associated Links:

Urine Collection Procedure

Collection Instructions

Specimen:Urine, timed collection (12 to 24 hour, 2-12 hour collections are acceptable but not recommended)
Optimal Volume:Submit entire collection; analysis requires 0.2 mL
Container:3 L plastic jug
Collection Instructions:Refrigerate during collection. IVP dye does not interfere with sample analysis.
Patient Preparation:The patient should continue good hydration and avoid cooked meat, coffee, tea or drugs (especially cephalotoxin and other cephalosporins) throughout the collection period.
Causes for Rejection:No serum creatinine collected; collection not timed.

Processing and Shipping

Specimen Processing:Mix collection well before aliquot is taken. Centrifuge specimens containing cells or precipitate. Aliquot 1 mL, 0.1 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Stability:Acceptable preservatives: NaF, glacial acetic, HCl or boric acid. Results should be inspected for consistency, assuming a normal collection should contain 1 g creat/24 hour. Collection on ice preferred; but not required. A clearance will be accepted and reported on patients whose serum creatinine is normal and has been collected within 72 hours of the urine collection. SI Unit Conversion Factor: clearance (mL/min) x 0.01667 = clearance (mL/s).
Test Performed at or Referral Lab Chemistry  (University of Minnesota Health Maple Grove Clinics, Fairview Lakes - FLMC)


Reference Range:

Standard Clearance

(calibrated to IDMS)


100-160 mL/min/1.73m2


110-180 mL/min/1.73m2

The calculation for standard creatinine clearance in mL/min=urine volume/minute x urine creatinine/serum creatinine x 1.73/surface area of body in m2. Body surface area is obtained from nomograms which require height and weight.


Use:Evaluate renal function.

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