Tacrolimus Area Under the Curve

Sunquest Code:TAAUC  
Epic Code:LAB3184Epic Name:Tacrolimus AUC
Synonyms:FK-506; Prograf
Methodology:Liquid chromatography/tandem mass spectrometry
Turnaround Time:Performed daily; results are reported the next day.
Special Instructions:Collect drug levels at baseline, 2 hours, 3 hours and 4 hours post dose. Order as individual TACR levels and send to laboratory immediately following collection. Only order one TAAUC (area under the curve) calculation per patient.

Collection Instructions

Optimal Volume:2 mL
Minimum\Peds Volume:0.4 mL
Container:Purple (EDTA) (Green (lithium heparin, no gel), Green (sodium heparin, no gel))
Collection Instructions:Collect levels at baseline, 2 hours, 3 hours and 4 hours post dose.

Processing and Shipping

Specimen Processing:Whole blood. Do not process. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Stability:Up to 14 days at room temperature (19-26ºC) or refrigerated (2-8ºC). For longer storage, freeze at -10ºC or colder.
Test Performed at or Referral Lab Drug Analysis  (UMMC-East Bank)


Therapeutic Range:120-160 ug*h/L
Use:Pharmacokinetics of Tacrolimus.

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