Cyclosporine Area Under the Curve
Abbrev Code: | CYAUC | ||
Order Code: | LAB3050 | Order Name: | Cyclosporine AUC Calculation |
Synonyms: | Cyclosporine AUC | ||
Methodology: | Liquid chromatography/tandem mass spectrometry | ||
CPT Codes: | 80158 x1 | ||
Turnaround Time: | Performed daily; results are reported the next day. | ||
Special Instructions: | Collect drug levels at baseline, 2 hours, 3 hours and 4 hours post dose. Order as individual levels and send to laboratory immediately following collection. Only order one CYAUC (area under the curve) calculation per patient. |
Collection Instructions
Specimen: | Blood |
Optimal Volume: | 2 mL |
Minimum\Peds Volume: | 1.2 mL |
Container: | Purple (EDTA) Alternate Containers: Green (lithium heparin, no gel), Green (sodium heparin, no gel) |
Collection Instructions: | Collect levels at baseline, 2 hours, 3 hours and 4 hours post dose. |
Causes for Rejection: | Collected in gel tube; clotted specimen. |
Processing and Shipping
Specimen Processing: | Whole blood. Do not process. Store in refrigerator. |
Shipping Instructions: | Ship at room temperature. |
Stability: | Specimens are stable refrigerated or at room temperature for at least two weeks. |
Test Performed at or Referral Lab | Drug Analysis (UMMC East Bank) |
Interpretive
Therapeutic Range: | 4000-6000 ug*h/L |
Use: | Pharmacokinetics of cyclosporine. |
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