Alpha-1-Antitrypsin, Blood
Abbrev Code: | AAT | ||
Order Code: | LAB810 | Order Name: | Alpha 1 Antitrypsin, Total |
Synonyms: | Alpha-1-Protease Inhibitor; Trypsin Inhibitory Capacity | ||
Methodology: | Immunoturbidimetry | ||
CPT Codes: | 82103 x1 | ||
Turnaround Time: | Performed twice a week; results are reported the same day. |
Collection Instructions
Specimen: | Blood |
Optimal Volume: | 1 mL |
Minimum\Peds Volume: | 0.6 mL |
Container: | Red or gold (gel) Alternate Containers: Red (no gel) |
Causes for Rejection: | Grossly hemolyzed and highly lipemic samples. Samples not separated form cells within 2 hours of collection. |
Processing and Shipping
Specimen Processing: | Within 2 hours centrifuge and aliquot 0.5 mL, 0.2 mL minimum. Store in freezer. |
Shipping Instructions: | Ship on dry ice. |
Stability: | After separation from cells: 2 days refrigerated; indefinitely frozen. |
Test Performed at or Referral Lab | UM Specialty Core/Prot/Endo (Optilite C) |
Interpretive
Reference Range: | 90-200 mg/dL |
Use: | Detection of hereditary decreases in production. Order when serum alpha1 globulin is low. Heterozygous patients are commonly about 60% of normal. Homozygous recessive patients exhibit levels about 10% of normal. |
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