Alpha-1-Antitrypsin, Blood
| Abbrev Code: | AAT | ||
| Order Code: | LAB810 | Order Name: | Alpha 1 Antitrypsin, Total |
| Synonyms: | Alpha-1-Protease Inhibitor; Trypsin Inhibitory Capacity | ||
| Methodology: | Immunoturbidimetry | ||
| CPT Codes: | 82103 x1 | ||
| Turnaround Time: | Performed twice a week; results are reported the same day. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 1 mL |
| Minimum\Peds Volume: | 0.6 mL |
| Container: | Red or gold (gel) Alternate Containers: Red (no gel) |
| Causes for Rejection: | Grossly hemolyzed and highly lipemic samples. Samples not separated form cells within 2 hours of collection. |
Processing and Shipping
| Specimen Processing: | Within 2 hours centrifuge and aliquot 0.5 mL, 0.2 mL minimum. Store in freezer. |
| Shipping Instructions: | Ship on dry ice. |
| Stability: | After separation from cells: 2 days refrigerated; indefinitely frozen. |
| Test Performed at or Referral Lab | UM Specialty Core/Prot/Endo (Optilite C) |
Interpretive
| Reference Range: | 90-200 mg/dL |
| Use: | Detection of hereditary decreases in production. Order when serum alpha1 globulin is low. Heterozygous patients are commonly about 60% of normal. Homozygous recessive patients exhibit levels about 10% of normal. |
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