Voriconazole
| Abbrev Code: | VCON | ||
| Order Code: | LAB5992 | Order Name: | Voriconazole Level |
| Synonyms: | Vfend | ||
| Methodology: | Liquid chromatography-Tandem mass spectrometry (LC/MS/MS) | ||
| CPT Codes: | 80285 x1 | ||
| Turnaround Time: | Performed Tuesday and Thursday; results are reported the same day. The cutoff time for same day reporting is 9:30 am on Tuesday, and 11:00 am on Thursday. | ||
| Special Instructions: | Trough level monitoring is recommended. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2 mL |
| Minimum\Peds Volume: | 0.6 mL |
| Container: | Purple (EDTA) Alternate Containers: Green (lithium heparin, no gel), Green (sodium heparin, no gel), Red (no gel) |
| Causes for Rejection: | Collected in a gel tube. |
Processing and Shipping
| Specimen Processing: | Within 2 hours of collection, centrifuge and aliquot 1 mL, 0.2 mL minimum. Freeze immediately. |
| Shipping Instructions: | Ship on dry ice. |
| Stability: | 2 hours room temperature; 1 week refrigerated; 2 weeks frozen |
| Test Performed at or Referral Lab | UM Special Drug/BGEN (Azole Z) |
Interpretive
| Critical Range: | Greater than 6.0 ug/mL |
| Reference Range: |
1.0-5.5 µg/mL. Trough level (collected immediately prior to next dose) is recommended.
|
| Use: | Monitor therapeutic drug level of voriconazole; evaluate voriconazole toxicity. |
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