2,3 Dinor 11 Beta Prostaglandin F2 Alpha, Timed Urine


Abbrev Code:23BPT   
Order Code:LAB6702Order Name:2,3 Dinor 11 Beta Prostaglandin F2 Alpha, Timed Urine
Methodology:Liquid chromatography/Tandem mass spectrometry, enzymatic colorimetric assay
CPT Codes: 84150 x1, 83570 x1
Turnaround Time:Specimens are sent to reference laboratory Mon-Fri; results are reported within 2-6 days.
Special Instructions:Include volume and duration of collection.
Compliance:

This test was developed and its performance characteristics determined by Laboratory Medicine and Pathology, Mayo Clinic. This test has not been cleared by the U.S. Food and Drug Administration.

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Urine Collection Procedure



Collection Instructions

Specimen:Urine, 24 hour timed collection
Optimal Volume:Submit entire collection, analysis requires 4 mL.
Minimum\Peds Volume:3 mL
Container:3 L plastic jug
Collection Instructions:Place specimen on ice or in refrigerator during collection.
Patient Preparation:Patients taking aspirin or nonsteroidal anti-inflammatory drugs (NSAID) may have decreased concentrations of prostaglandin F2 alpha. If possible, discontinue for 2 weeks or 72 hours, respectively, prior to collecting a specimen,
Causes for Rejection:Room temperature specimens. All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.


Processing and Shipping

Specimen Processing:Mix collection well before aliquot is taken, Aliquot 5 mL, 4 mL minimum, and record collection volume on aliquot tube. Store refrigerated (preferred).
Shipping Instructions:Ship refrigerated.
Stability:8 hours at room temperature; 14 days refrigerated (preferred); 30 days frozen.
Test Performed at or Referral Lab Lab Sendouts  (Mayo)
Referral Lab number:23BPT


Interpretive

Reference Range:Less than 1802 pg/mg creatinine
Limitations:Elevated levels of 2,3 -dinor-11beta-prostaglandin F2 alpha (2,3 BPG) in urine are not specific for systemic mast cell disease and may be found in patients with angiodema, diffuse urticaria, or myeloproliferative diseases in the absence of diffuse mast cell proliferation.
Use:Screening for mast cell activation disorders including systemic mastocytosis using 24 hour urine specimens.


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