Alpha Fetoprotein (AFP), Total and L3 Percent

Abbrev Code:AFPL3   
Order Code:LAB4396Order Name:Alpha Fetoprotein, Total & L3 Percent
Synonyms:Hepatocellular Carcinoma AFP (Total and L3%)
Methodology:Immunoassay/liquid chromatography
CPT Codes: 82107 x1
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported within 1-5 days.

Collection Instructions

Optimal Volume:2 mL
Minimum\Peds Volume:1.2 mL
Container:Red or gold (gel)
Alternate Containers: Red (no gel)
Causes for Rejection:Plasma sample

Processing and Shipping

Specimen Processing:Centrifuge and aliquot within 2 hours of collection 1 mL, 0.5 mL minimum. Samples are stable refrigerated for 5 days. Store in freezer.
Shipping Instructions:Ship on dry ice.
Stability:8 hours at room temperature; 5 days refrigerated; 3 months frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:81208


Reference Range:

Alpha Fetoprotein Total

0-15 ng/mL

Alpha Fetoprotein L3 Percent

0-9.9 percent



Use:The Wako LiBASys method is used. Results obtained with different assay methods or kits cannot be used interchangeably. The Wako AFP-L3% assay is intended as a risk assessment test for the development of hepatocellular carcinoma in patients with chronic liver diseases. Elevated AFP-l3% values have been sown to be associated with a seven-fold increase in the risk of developing hepatocellular carcinoma within the next 21 months. Patients with elevated serum AFP-L3% should be more intensely evaluated for evidence of hepatocellular carcinoma. The result is not interpretable as a tumor marker in pregnant females.

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