Sensorimotor Neuropathy Profile with Recombx-Complete
| Sunquest Code: | GM1QAT | ||
| Epic Code: | LAB5573 | Epic Name: | Sensorimotor Neuropathy Panel |
| Synonyms: | Gait Ataxia Late Onset Polyneuropathy (GALOP) | ||
| Methodology: | Enzyme-linked immunosorbent assay, Automated Nanoliter Scale immunoassay and Western Blot | ||
| Test Includes: | Co-GM1 autoantibody, GALOP Antibody Test, MAG Dual Antigen Autoantibody Test, Recombx Hu autoantibody Test, Sulfatide Autoantibody Test. Co-Asialo Autoantibody Test, Co-GD1b Autoantibody Test, GD1a | ||
| Turnaround Time: | Specimens are sent to the reference laboratory Mon-Fri; results are reported within 7-10 days. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 4 mL |
| Minimum\Peds Volume: | 1.2 mL |
| Container: | Red (no gel) [Alternate Containers: Red or gold (gel)] |
| Causes for Rejection: | Hemolyzed, icteric or lipemic specimens. Serum must be separated from cells within 48 hours of collection. |
Processing and Shipping
| Specimen Processing: | Centrifuge and aliquot 2 mL, 0.5 mL minimum. Store in refrigerator. |
| Shipping Instructions: | Ship at refrigerated temperature. |
| Stability: | 3 days at room temperature; 21 days refrigerated; 28 days frozen. |
| Test Performed at or Referral Lab | Lab Sendouts (Athena Diagnostics) |
| Referral Lab number: | 3100 |
Interpretive
| Reference Range: | By report. |
| Use: |
Anti-MAG, anti-SGPG, anti-GM1, anti-GD1a, anti-GD1b, anti-asialo GM1 and anti-sulfatide, anti-Hu and IgM GALOP antibodies are found in patients with a peripheral neuropathy and mixed sensory and motor symptoms. This semi-quantitative assay may be useful in monitoring therapeutic responses in select cases.
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