Hyperoxaluria Panel, Urine


Sunquest Code:HYOX  
Epic Code:LAB6308Epic Name:Hyperoxaluria Panel, Urine
Synonyms:Hyperoxaluria Type 1 and 2
Methodology:Gas chromatography/Mass spectrometry (GC-MS)
Turnaround Time:Specimens are sent to reference laboratory Mon-Fri; results are reported within 14 days.
Compliance:

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.
Associated Links:

Urine Collection Procedure


Collection Instructions

Specimen:Urine
Optimal Volume:10 mL
Minimum\Peds Volume:1.1 mL
Container:Plastic leakproof container, sterile
Collection Instructions:Have patient void the first- morning specimen, then collect specimen within 2 hours of first morning void while patient continues to fast. Fluids are allowed.
Patient Preparation:Fasting specimen (12-14 hours) is required.
Causes for Rejection:Preserved specimen.


Processing and Shipping

Specimen Processing:Mix collection well before aliquot is taken. Aliquot 10 mL, 1.1 mL minimum. Freeze immediately.
Shipping Instructions:Ship on dry ice (preferred).
Stability:Stability: 14 days refrigerated; 90 days frozen.
Test Performed at or Referral Lab Lab Sendouts  (Mayo)
Referral Lab number:HYOX


Interpretive

Reference Range:
Glycolate  
Less than or equal to 17 y Less than or equal to 75 mg/g creatinine
Greater than or equal to 18 y Less than or equal to 50 mg/g creatinine
 
Glycerate  
Less than or equal to 31 days Less than or equal to 75 mg/g creatinine
32 days - 4 y Less than or equal to 125 mg/g creatinine
5-10 y Less than or equal to 55 mg/g creatinine
Greater than or equal to 11 y Less than or equal to 25 mg/g creatinine
 
Oxalate  
Less than or equal to 6 mo Less than or equal to 400 mg/g creatinine
7 mo - 1 y Less than or equal to 300 mg/g creatinine
2 - 6  y Less than or equal to 150 mg/g creatinine
7 - 10 y Less than or equal to 100 mg/g creatinine
Greater than or equal to 11 y Less than or equal to 75 mg/g creatinine
 
4-hydroxy-2-oxoglutarate (HOG) Less than or equal to 10 mg/g creatinine
 
Use:Distinguishing between primary and secondary hyperoxaluria.


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