Free Kappa and Lambda Light Chains, Quantitative, Urine
| Abbrev Code: | ARMISC | ||
| Order Code: | LAB4909 | Order Name: | Send Outs Misc Test |
| Synonyms: | Immunofixation with Free Light Chains, Quantitative; Kappa, Lambda Light Chains, Bence Jones Proteins | ||
| Methodology: | Immunofixation electrophoresis; Immunoturbidimetry | ||
| CPT Codes: | 83520 x2, 84156 x1, 86335 x1 | ||
| Turnaround Time: | Specimens are sent to the reference laboratory Mon-Sat; results are reported within 2-6 days. | ||
| Associated Links: | |||
Collection Instructions
| Specimen: | Urine, 24 hour collection or random |
| Optimal Volume: | Submit entire 24 collection; analysis requires 4 mL minimum |
| Container: | Plastic leakproof container, sterile |
| Collection Instructions: | Refrigerate during collection. |
| Causes for Rejection: | Room temperature specimens. |
Processing and Shipping
| Specimen Processing: | Mix collection well before aliquot is taken. Transfer specimen to two 4 mL aliquots; one 4 mL aliquot minimum. Store in refrigerator. Record total volume and collection time interval on transport tube and test request form. |
| Shipping Instructions: | Ship at refrigerated temperature. |
| Stability: | 3 weeks refrigerated; 6 months frozen. |
| Test Performed at or Referral Lab | Lab Sendouts (ARUP) |
| Referral Lab number: | 3002104 |
Interpretive
| Reference Range: |
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| Use: | Results of urine free light chain testing can be used to monitor disease progression or response to therapy in patients for whom urine electrophoresis is unable to provide reliable Bence Jones Protein quantification. The results of urine kappa and lambda free light chain quantitative values may be misleading in specimens with high levels of urinary polyclonal free light chains, and absent Bence Jones protein by immunofixation; therefore correlation with urine immunofixation is required to identify inconsistent results. |
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