BRCA2, Single Site Analysis
| Sunquest Code: | BRCO2 | ||
| Epic Code: | LAB6948 | Epic Name: | BRAC2 Single Site |
| Synonyms: | BRCA2 Analysis Known Mutation; Familial; Level 2; Breast | ||
| Methodology: | Sanger sequencing | ||
| Turnaround Time: | Testing is performed Mon-Fri; results are reported within 21 days. | ||
| Special Instructions: | A signed informed consent in the patient's medical record is required. The consent should not be sent to the laboratory. The link to the Genetic Testing Consent Form is provided as a convenience for the providers and genetic counselors.
Bone Marrow Transplant Patients: If a patient is the recipient of an allogeneic transplant, this test must be done on a pre-transplant sample. Contact the Molecular Diagnostics lab to see if a pre-transplant sample is available. |
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| Associated Links: | Genetic Testing Consent Form, MD Hereditary Order Instructions |
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Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 10 mL |
| Minimum\Peds Volume: | 3 mL |
| Container: | Yellow (ACD, Solution A) tube available from laboratory (Purple (EDTA)) |
| Causes for Rejection: | Frozen or clotted specimen, incorrect anticoagulant, specimen more than 5 days old. Sample collected from bone marrow transplant recipient, Samples tested in hematology using automated instrumentation not accepted. DNA extracted at non-CLIA certified (or equivalent) lab. |
Processing and Shipping
| Specimen Processing: | Do not process. Store at room temperature. |
| Shipping Instructions: | Ship at room temperature. |
| Stability: | 5 days at room temperature. |
| Test Performed at or Referral Lab | Molecular Diagnostics (UMMC-East Bank) |
Interpretive
| Reference Range: | By report. |
| Use: | This testing is used to identify inherited risks for cancers in patients with a clinical presentation and/or family history strongly suggestive of a hereditary cancer predisposition. This testing is typically performed through a genetic counselor and many insurance companies required documentation of genetic counseling in order for the testing to be covered. |
Click HERE to Report test errors or omissions.
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