Lacosamide Level
| Abbrev Code: | LACOSA | ||
| Order Code: | LAB6978 | Order Name: | Lacosamide Level |
| Synonyms: | Vimpat | ||
| Methodology: | High performance liquid chromatography/Tandem mass spectrometry | ||
| CPT Codes: | 80235 x1 | ||
| Turnaround Time: | Specimens are sent to the reference laboratory Sun-Sat; results are reported within 1-4 days. | ||
| Compliance: | For tests developed and validated by ARUP (previously referred to as Compliance Statement B, C or D). This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the U.S. Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes. |
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Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2 mL |
| Minimum\Peds Volume: | 1.2 mL |
| Container: | Red (no gel) Alternate Containers: Purple (EDTA) |
| Collection Instructions: | Trough level is preferred; collect immediately before dose, but no sooner than 2 hours before. |
| Causes for Rejection: | Whole blood. Gel separator tubes. Light blue (citrate) or yellow (SPS or ACD solution). |
Processing and Shipping
| Specimen Processing: | Within 2 hours of collection, centrifuge and aliquot 1 mL, 0.5 mL minimum. Store at room temperature. |
| Shipping Instructions: | Ship at refrigerated temperature. |
| Stability: | 15 days at room temperature, refrigerated or frozen. |
| Test Performed at or Referral Lab | Lab Sendouts (ARUP) |
| Referral Lab number: | 2003182 |
Interpretive
| Critical Range: | Toxic level: Greater than or equal to 20 μg/mL |
| Therapeutic Range: | 1.0-10.0 μg/mL |
| Use: | Lacosamide is an anticonvulsant drug indicated for adjunctive therapy for partial-onset seizures. The therapeutic range is based on serum, predose (trough) draw collection at a steady-state concentration. |
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