Proinsulin, Intact


Abbrev Code:PROINS   
Order Code:LAB5978Order Name:Proinsulin
Methodology:Chemiluminescent immunoassay
CPT Codes: 84206 x1
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported within 1-6 days.
Special Instructions:Do not use to diagnose diabetes mellitus.
Compliance:

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the U.S. Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.



Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:0.6 mL
Container:Red or gold (gel)
Alternate Containers: Purple (EDTA), Red (no gel)
Patient Preparation:Patient must fast for 12-15 hours prior to collection.
Causes for Rejection:Gross hemolysis


Processing and Shipping

Specimen Processing:Centrifuge and aliquot within 2 hours of collection 1 mL, 0.2 mL minimum. CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered. Store in freezer.
Shipping Instructions:Ship frozen on dry ice.
Stability:After separation from cells: 48 hours refrigerated; 2 months frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:70112


Interpretive

Reference Range:

0-17 y

Not established

18 y and older

Less than or equal to 8.0 pmol/L

 

 

Use:Aids in the detection of insulinoma. Do not use to diagnose diabetes mellitus.

Fasting intact proinsulin values above the reference interval indicate a possible insulin secreting pancreatic tumor (insulinoma) in patients with hypoglycemia. Fasting intact proinsulin values range from 3 to 50 pmol/L in patients with untreated type 2 diabetes.


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