Cytochrome P450 2C19 Genotype
| Abbrev Code: | MMMISC | ||
| Order Code: | LAB4909 | Order Name: | Laboratory Miscellaneous Order |
| Methodology: | Polymerase chain reaction (PCR)/with Allelic Discrimination | ||
| CPT Codes: | 81225 x1 | ||
| Turnaround Time: | Specimens are sent to reference laboratory Mon-Fri; results are reported within 1-5 days. | ||
| Special Instructions: | Transfusions will interfere with testing for up to 4-6 weeks. DNA obtained from white cells may not provide useful information for patients who received a recent transfusion of blood that was not leukocyte-reduced. Wait 4-6 weeks until transfused cells have left the patient's circulation before drawing the patient's blood specimen for genotype testing. A signed informed consent in the patient's medical record is required; the consent form should not be sent to the laboratory. See Associated Links. | ||
| Compliance: | This test was developed and its performance characteristics determined by Laboratory Medicine and Pathology, Mayo Clinic. This test has not been cleared by the U.S. Food and Drug Administration. |
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| Associated Links: | |||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 3 mL |
| Minimum\Peds Volume: | 0.4 mL |
| Container: | Purple (EDTA) |
Processing and Shipping
| Specimen Processing: | Whole blood. Do not process. Store at room temperature. |
| Shipping Instructions: | Ship in original container at room temperature. |
| Test Performed at or Referral Lab | Lab Sendouts (Mayo Medical Laboratories) |
| Referral Lab number: | 2C19V |
Interpretive
| Reference Range: | By report. |
| Use: | Identifying patients who may be at risk for altered metabolism of drugs that are modified by CYP2C19.
Predicting anticoagulation response to Clopidogrel. |
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