CD4 Plus T-Cell Recent Thymic Emigrants (RTE)


Abbrev Code:CD4RTE   
Order Code:LAB7011Order Name:CD4 T-Cell Recent Thymic Emigrants
Synonyms:T Cell Recent Thymic; CD4 RTE, Flow Cytometry; T cell
Methodology:Flow cytometry
CPT Codes: 86356 x3
Turnaround Time:Specimens are sent to reference laboratory Mon-Sun; results are reported within 1-4 days
Special Instructions:Specimen must be analyzed within 72 hours of collection. *Ordering physician name and phone number are required.
Compliance:

This test uses a manufacturer labeled Analyte Specific Reagent (ASR) as the reagent providing the specificity of the assay. The test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.


Collection Instructions

Specimen:Whole blood
Optimal Volume:4 mL
Minimum\Peds Volume:0.5 mL
Container:Purple (EDTA)
Alternate Containers: Green (sodium heparin, no gel)
Causes for Rejection:Cord blood. Specimens older than 72 hours. Clotted or hemolyzed specimens. Frozen specimens.


Processing and Shipping

Specimen Processing:Whole blood. Store at room temperature or refrigerated in original container.
Shipping Instructions:Ship at refrigerated temperature.
Stability:72 hours at room temperature or refrigerated.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:2010179


Interpretive

Reference Range:
% CD4+CD31+CD45RA+(RTEs)
Age Reference Interval
1 w - 2 mo 50-100% of CD4+
2 - 5 mo 64-94% of CD4+
5 - 9 mo 65-90% of CD4+
9 - 15 mo 61-93% of CD4+
15 - 24 mo 40-100% of CD4+
2 - 5 y 37-100% of CD4+
5 - 10 y 41-81% of CD4+
10-16 y 31-81% of CD4+
>16 y 6-51% of CD4+
  Abs CD4+CD31+CD45RA+(RTEs)
Age Reference Interval
1 w - 2 mo 1000-4900 cells/µL
2 - 5 mo 1400-5200 cells/µL
5 - 9 mo 800-6200 cells/µL
9 - 15 mo 900-5800 cells/µL
15 - 24 mo 170-7400 cells/µL
2 - 5 y 190-2600 cells/µL
5 - 10 y 200-1700 cells/µL
10-16 y 150-1500 cells/µL
>16 y 51-609 cells/µL
   
Use:Assess thymic function in suspected severe combined immunodeficiency (SCID), DiGeorge syndrome and other T-cell immune deficiency disorders. Evaluate immune reconstitution during highly active antiviral therapy (HAART) in HIC patients and post-chemotherapy and hematopoietic cell transplant.


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