Serotonin Receptor Genotype (HTR2A and HTR2C) - LG4987


Sunquest Code:MMMISC  
Epic Code:LAB4909Epic Name:Send Outs Misc Test
Synonyms:Serotonin Receptor 2A/2C Genotype
Methodology:Polymerase chain reaction (PCR) with allele discrimination analysis
Turnaround Time:Specimens are sent to reference laboratory Mon-Fri; results are reported within 2-8 days.
Special Instructions:Bone marrow transplants will interfere with testing. Call Mayo Medical Laboratories at 800-533-1710 or 507-266-5700 for instructions. Transfusions will interfere with testing for up to 4 to 6 weeks. DNA obtained from white cells may not provide useful information for patients who received a recent transfusion of blood that was not leukocyte-reduced. Wait 4 to 6 weeks until transfused cells have left the patient's circulation before drawing the patient's blood specimen for genotype testing. A signed informed consent in the patient's medical record is required; the consent form should not be sent to the laboratory. See Associated Links.
Compliance:

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.
Associated Links:

Genetic Testing Consent Form


Collection Instructions

Specimen:Blood
Optimal Volume:3 mL
Minimum\Peds Volume:0.4 mL
Container:Purple (EDTA)


Processing and Shipping

Specimen Processing:Whole blood. Do not process. Store at room temperature (preferred) or refrigerated temperature.
Shipping Instructions:Ship in original container at room temperature (preferred) or refrigerated temperature.
Test Performed at or Referral Lab Lab Sendouts  (Mayo Medical Laboratories)
Referral Lab number:HTR2V


Interpretive

Reference Range:By report.
Use:Guiding antidepressant and antipsychotic drug selection.


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