Chromatin Antibody, IgG

Abbrev Code:ARMISC   
Order Code:LAB4909Order Name:Laboratory Miscellaneous Order
Synonyms:Anti-Chromatin Aby; Nucleosomal Aby; Chromatin DNL
Methodology:Enzyme linked immunosorbent assay
CPT Codes: 86235 x1
Turnaround Time:Specimens are sent to the reference laboratory Mon-Sun; results are reported within 1-4 days.

Collection Instructions

Optimal Volume:1 mL
Minimum\Peds Volume:0.8 mL
Container:Red or gold (gel)
Alternate Containers: Red (no gel)
Causes for Rejection:Urine or plasma. Contaminated, heat-inactivated; severely hemolyzed, icteric or lipemic specimens.

Processing and Shipping

Specimen Processing:Centrifuge ASAP or within 2 hours of collection and aliquot 0.5 mL, 0.3 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Stability:After separation from cells: 48 hours at room temperature; 2 weeks refrigerated; 1 year frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:2005287


Reference Range:
19 Units or less Negative
20-60 Units Moderate Positive
61 Units or greater Strong Positive
The presence of anti-chromatin antibodies may be useful in the diagnosis of systemic lupus erythematosus (SLE) or drug induced lupus (DIL) and have been reported to be predictive of lupus nephritis, especially when antibody levels are high.
Use:Aids in the diagnosis of systemic lupus erythematosus (SLE).

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