Chromatin Antibody, IgG


Sunquest Code:ARMISC  
Epic Code:LAB4909Epic Name:Send Outs Misc Test
Synonyms:Anti-Chromatin Aby; Nucleosomal Aby; Chromatin DNL
Methodology:Enzyme linked immunosorbent assay
CPT Code:----------CPTCODES HERE----------
Turnaround Time:Specimens are sent to the reference laboratory Mon-Sat; results are reported within 1-4 days.


Collection Instructions

Specimen:Blood
Optimal Volume:1 mL
Minimum\Peds Volume:0.8 mL
Container:Red or gold (gel) (Red (no gel))
Causes for Rejection:Urine or plasma. Contaminated, heat-inactivated; severely hemolyzed, icteric or lipemic specimens.


Processing and Shipping

Specimen Processing:Within 2 hours of collection, centrifuge and aliquot 0.5 mL, 0.3 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Stability:After separation from cells: 48 hours at room temperature; 2 weeks refrigerated; 1 year frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:2005287


Interpretive

Reference Range:
19 Units or less Negative
20-60 Units Moderate Positive
61 Units or greater Strong Positive
The presence of anti-chromatin antibodies may be useful in the diagnosis of systemic lupus erythematosus (SLE) or drug induced lupus (DIL) and have been reported to be predictive of lupus nephritis, especially when antibody levels are high.
Use:Aids in the diagosis of systemic lupus erythematosus (SLE).


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