Myeloperoxidase and Proteinase 3 Panel
| Sunquest Code: | VASPAN | ||
| Epic Code: | LAB6360 | Epic Name: | Myeloperoxidase and Proteinase 3 Panel |
| Synonyms: | Myeloperoxidase (MPO) Antibody, IgG; Proteinase 3 (PR3) Antibody, IgG; Anti-Neutrophil Cytoplasmic Antibodies; Autoantibodies | ||
| Methodology: | Multiplex flow immunoassay | ||
| Test Includes: | Test orders codes: MPOIGG and PR3IGG. When possible, order specific individual antibodies if entire panel is not needed. | ||
| Turnaround Time: | Performed Mon-Fri; results reported the same day. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2 mL |
| Minimum\Peds Volume: | 0.9 mL |
| Container: | Red or gold (gel) (Red (no gel)) |
| Causes for Rejection: | Gross hemolysis |
Processing and Shipping
| Specimen Processing: | Centrifuge ASAP and aliquot 1 mL, 0.35 mL minimum. Store in refrigerator up to 7 days. |
| Shipping Instructions: | Ship at refrigerated temperature. |
| Test Performed at or Referral Lab | Specialty Core (UMMC-East Bank) |
Interpretive
| Reference Range: |
Antibody index (AI) values reflect qualitative changes in antibody concentration that cannot be directly associated with clinical condition or disease state.
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| Use: | Aids in the diagnosis of antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitides: Microscopic Polyangiitis (MPA), Necrotising Gomerulonephritis, Churg-Strauss Syndrome and Wegener's Granulomatosis. |
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