Myeloperoxidase and Proteinase 3 Panel

Sunquest Code:VASPAN  
Epic Code:LAB6360Epic Name:Myeloperoxidase and Proteinase 3 Panel
Synonyms:Myeloperoxidase (MPO) Antibody, IgG; Proteinase 3 (PR3) Antibody, IgG; Anti-Neutrophil Cytoplasmic Antibodies; Autoantibodies
Methodology:Multiplex flow immunoassay
Test Includes:Test orders codes: MPOIGG and PR3IGG. When possible, order specific individual antibodies if entire panel is not needed.
Turnaround Time:Performed Mon-Fri; results reported the same day.

Collection Instructions

Optimal Volume:2 mL
Minimum\Peds Volume:0.9 mL
Container:Red or gold (gel) (Red (no gel))
Causes for Rejection:Gross hemolysis

Processing and Shipping

Specimen Processing:Centrifuge ASAP and aliquot 1 mL, 0.35 mL minimum. Store in refrigerator up to 7 days.
Shipping Instructions:Ship at refrigerated temperature.
Test Performed at or Referral Lab Specialty Core  (UMMC-East Bank)


Reference Range:


Reference Interval

Myeloperoxidase (MPO) Antibody, IgG

Negative: Less than 1.0 AI

Positive: 1.0 AI or greater

Proteinase 3 (PR3) Antibody, IgG

Negative: Less than 1.0 AI

Positive: 1.0 AI or greater

Antibody index (AI) values reflect qualitative changes in antibody concentration that cannot be directly associated with clinical condition or disease state.


Use:Aids in the diagnosis of antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitides: Microscopic Polyangiitis (MPA), Necrotising Gomerulonephritis, Churg-Strauss Syndrome and Wegener's Granulomatosis.

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