Smith/RNP (ENA) Antibody, IgG


Abbrev Code:ARMISC   
Order Code:LAB4909Order Name:Send Outs Misc Test
Synonyms:mRNP Antibody IgG
Methodology:Multiplex bead assay
CPT Codes: 86235 x1
Turnaround Time:Specimens are sent to the reference laboratory Mon-Sat; results are reported within 1-2 days.


Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:0.6 mL
Container:Red or gold (gel)
Alternate Containers: Red (no gel)
Causes for Rejection:Plasma or other body fluids, Contaminated, hemolyzed, or severely lipemic specimens.


Processing and Shipping

Specimen Processing:Within 2 hours of collection, centrifuge and aiquot 1 mL, 0.2 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Stability:After separation from cells: 48 hours at room temperature; 2 weeks refrigerated; 1 year frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)


Interpretive

Reference Range:
29 AU/mL or less Negative
30-40 AU/mL Equivoca
41 AU/mL or greater Positive
Smith/RNP antibodies are frequently seen in patients with mixed connective tissue disease (MCTD) and are also associated with other systemic autoimmune rheumatic diseases (SARDS) such as systemic lupus erytheatosus (SLE), systemic sclerosis, and myositis. Antibodies targeting the Smith/RNP antibody response must be considered when interpreting these results.
Use:Diagnosis of systemic autoimmune disease.


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