PSA, Tumor Marker


Abbrev Code:PSA   
Order Code:LAB3695Order Name:PSA Tumor Marker
Synonyms:PSA Screen; Prostatic Specific Antigen
Methodology:Chemiluminescence
CPT Codes: 84153 x1
Turnaround Time:Varies by site.


Collection Instructions

Specimen:Blood
Optimal Volume:2.5 mL
Minimum\Peds Volume:0.6 mL
Container:Green (lithium heparin, gel), St. Joseph - Red (no gel)
Alternate Containers: Red (no gel), Red or gold (gel)
Contraindications:Large doses of biotin (10 mg or more per day) may cause clinically significant interference in PSA tumor marker levels. If interference is suspected, it is strongly recommended that biotin is discontinued for at least one week prior to retesting.


Processing and Shipping

Specimen Processing:Centrifuge and aliquot within 4 hours of collection 1.25 mL, 0.2 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature. Alternatively, ship on dry ice.
Stability:7 days refrigerated; up to 4 months frozen at -80°C.
Test Performed at or Referral Lab Chemistry  (CSC Maple Grove, Range, UMMC East, Oxboro Clinic, Lakes, Northland, Clinics, CSC Mpls, Grand Itasca, St. Joseph's)


Interpretive

Reference Range:0-4 ug/L
The Siemens Dimension Vista® method is used. Results obtained with different assay methods or kits cannot be used interchangeably.
Use:Elevated in many patients with prostate cancer, as well as in some patients with prostatic hypertrophy. Primarily used to track progression of prostatic carcinoma, monitor therapeutic response, and identify recurrence of disease. Half life is approximately 2 days.


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