Leflunomide Metabolite, Serum or Plasma
| Abbrev Code: | LEFMET | ||
| Order Code: | LAB6671 | Order Name: | Leflunomide Metabolite |
| Methodology: | High performance liquid chromatography/Mass spectrometry | ||
| CPT Codes: | 80193 x1 | ||
| Turnaround Time: | Specimens are sent to reference laboratory Mon-Sat; results are reported within 1-6 days. | ||
| Compliance: | For tests developed and validated by ARUP (previously referred to as Compliance Statement B, C or D). This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the U.S. Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes. |
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Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2 mL |
| Minimum\Peds Volume: | 0.6 mL |
| Container: | Red (no gel) Alternate Containers: Green (sodium heparin, no gel), Gray (sodium fluoride + potassium oxalate), Purple (EDTA) |
| Patient Preparation: | Timing of specimen collection: Predose (trough). Obtain specimen 12-24 hours after last dose. |
| Causes for Rejection: | Collection in a potassium oxalate or serum separator tube; whole blood. |
Processing and Shipping
| Specimen Processing: | Centrifuge and aliquot 1 mL, 0.2 mL minimum within 2 hours of collection. Store in refrigerator. |
| Shipping Instructions: | Ship at refrigerated temperature. Room temperature or frozen is also acceptable. |
| Stability: | 7 days at room temperature; 17 days refrigerated; 90 days frozen, |
| Test Performed at or Referral Lab | Lab Sendouts (ARUP) |
| Referral Lab number: | 2007460 |
Interpretive
| Reference Range: | Therapeutic and toxic ranges are not well established. Concentrations greater than 40.000 ug/mL tend to correlate with improved patient outcome. A proposed therapeutic range is 50.000-100.000 ug/mL. |
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