Amikacin Level
| Sunquest Code: | AMIK | ||
| Epic Code: | LAB145 | Epic Name: | Amikacin Level |
| Methodology: | Immunoassay | ||
| Turnaround Time: | Performed and reported 24 hours/day. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2 mL |
| Minimum\Peds Volume: | 1.2 mL |
| Container: | Red (no gel) [Alternate Containers: Purple (EDTA)] |
| Collection Instructions: | Trough levels: Collect immediately prior to the next dose. Peak levels: Collect 60 minutes after the end of IV infusion; 1-2 hours if decreased renal function. |
| Causes for Rejection: | Processed >4 hours after collection and the patient is receiving beta-lactam antibiotics or cephalosporins. Gross hemolysis. |
Processing and Shipping
| Specimen Processing: | Centrifuge and aliquot 1 mL, 0.5 mL minimum. Indicate peak and trough level. |
| Shipping Instructions: | Ship at refrigerated temperature. |
| Test Performed at or Referral Lab | Chemistry (UMMC-East Bank) |
Interpretive
| Critical Range: | Greater than 50 mg/L |
| Reference Range: | Trough: Less than 5 mg/L Peak: 15-30 mg/L |
| Use: | Monitor therapeutic dosing and evaluate toxicity of amikacin. |
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