PM/ScL-100 Antibody, IgG, by Immunoblot
| Abbrev Code: | PMSCL | ||
| Order Code: | LAB6490 | Order Name: | PM/SCL 100 Ab IgG with Reflex to ANA IFA |
| Synonyms: | PM SCL 100 Antibody | ||
| Methodology: | Immunoblot | ||
| CPT Codes: | 86235 x1 | ||
| Turnaround Time: | Specimens are sent to reference laboratory Mon-Sat; results are reported within 1-9 days. | ||
| Compliance: | For tests developed and validated by ARUP (previously referred to as Compliance Statement B, C or D). This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the U.S. Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes. |
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Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2 mL |
| Minimum\Peds Volume: | 0.8 mL |
| Container: | Red or gold (gel) Alternate Containers: Red (no gel) |
| Causes for Rejection: | Plasma. Contaminated, hemolyzed or severely lipemic specimens. |
Processing and Shipping
| Specimen Processing: | Centrifuge and aliquot 1 mL, 0.3 mL minimum. Store in refrigerator. |
| Shipping Instructions: | Ship at refrigerated temperature. |
| Stability: | After separation from cells: 48 hours at room temperature; 2 weeks refrigerated; 1 year frozen. |
| Test Performed at or Referral Lab | Lab Sendouts (ARUP) |
| Referral Lab number: | 2003040 |
Interpretive
| Reference Range: | 5 units or less: Negative 6-10 units: Borderline 11 units or greater: Positive |
| Use: | The presence of PM/Scl-100 IgG antibody along with a positive ANA IFA nucleolar pattern is associated with connective tissue diseases such as polymyositis (PM), dermatomyositis (DM), systemic sclerosis (SSc), and polymyositis/systemic sclerosis overlap syndrome. |
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