ADAMTS13 Activity
| Sunquest Code: | ADAMAT | ||
| Epic Code: | LAB6838 | Epic Name: | ADAMTS13 Activity |
| Synonyms: | VWF Cleaving Protease Activity | ||
| Methodology: | Fret-based Kinetic Assay | ||
| Turnaround Time: | Specimens are sent to the reference laboratory Mon-Fri; results are reported within 1-3 days. | ||
| Special Instructions: | Send platelet-poor plasma for testing. See Specimen Collection and Processing for Special Coagulation Specimens Associated Link. | ||
| Associated Links: | Specimen Collection and Processing for Coagulation Specimens |
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Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2.7 mL (in 3 mL tube) - filled to fill line on the tube |
| Minimum\Peds Volume: | 1.8 mL (in 2 mL tube) - filled to fill line on the tube |
| Container: | Blue Na Citrate, 3.2% - fill to fill line on tube |
| Causes for Rejection: | Over-filled or under-filled tubes. Hemolyzed or clotted specimens. EDTA plasma. |
Processing and Shipping
| Specimen Processing: | See Special Coagulation processing instructions. Aliquot 0.5 mL, 0.2 mL minimum. Store in freezer. |
| Shipping Instructions: | Ship on dry ice. |
| Stability: | Up to 7 days at room temperature or refrigerated; indefinitely frozen (preferred). |
| Test Performed at or Referral Lab | Lab Sendouts (Versiti) |
| Referral Lab number: | 1298 |
Interpretive
| Reference Range: | ADAMTS13 Activity: Greater than or equal to 67% |
| Use: | Diagnosis of congenital or idiopathic thrombotic thrombocytopenic purpura (TTP). |
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