Protein C, Total Antigen
| Abbrev Code: | PRCAGN | ||
| Order Code: | LAB6891 | Order Name: | Protein C Antigen |
| Methodology: | Immunoassay | ||
| CPT Codes: | 85302 x1 | ||
| Turnaround Time: | Specimens are sent to reference laboratory Mon-Sat; results are reported within 1-2 days. | ||
| Associated Links: | Specimen Collection and Processing for Coagulation Specimens |
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Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | Two 2.7 mL (in 3 mL tube) - filled to fill line on the tube |
| Minimum\Peds Volume: | One 2.7 mL (in 3 mL tube) - filled to fill line on the tube |
| Container: | Blue Na Citrate, 3.2% - fill to fill line on tube |
| Causes for Rejection: | Serum, EDTA plasma, clotted or hemolyzed specimens. |
Processing and Shipping
| Specimen Processing: | Centrifuge and aliquot 2 mL, 1 mL minimum. Freeze immediately. |
| Shipping Instructions: | Ship on dry ice. |
| Stability: | 3 months frozen on -20°C, and 6 months frozen on -70°C |
| Test Performed at or Referral Lab | Lab Sendouts (ARUP) |
| Referral Lab number: | 30111 |
Interpretive
| Reference Range: |
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| Limitations: | Patients on warfarin may have decreased Protein C values. Patients should be off Warfarin therapy for two weeks for accurate measurement of Protein C. | ||||||||||||||||
| Use: | Aids in diagnosis of congenital deficiencies characterized by recurrent venous thrombosis. Acquired deficiencies associated with Protein C includes: oral anticoagulant therapy, liver disease, vitamin K deficiency. Malignancy, consumptive DIC, surgery, trauma, antibodies to Protein C and hepatic immaturity of the newborn. |
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