Protein C, Total Antigen

Abbrev Code:PRCAGN   
Order Code:LAB6891Order Name:Protein C Antigen
CPT Codes: 85302 x1
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported within 1-2 days.
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Specimen Collection and Processing for Coagulation Specimens

Collection Instructions

Optimal Volume:Two 2.7 mL (in 3 mL tube) - filled to fill line on the tube
Minimum\Peds Volume:One 2.7 mL (in 3 mL tube) - filled to fill line on the tube
Container:Blue Na Citrate, 3.2% - fill to fill line on tube
Causes for Rejection:Serum, EDTA plasma, clotted or hemolyzed specimens.

Processing and Shipping

Specimen Processing:Centrifuge and aliquot 2 mL, 1 mL minimum. Freeze immediately.
Shipping Instructions:Ship on dry ice.
Stability:3 months frozen on -20°C, and 6 months frozen on -70°C
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:30111


Reference Range:

1-4 d


5-29 d


30-89 d


90-179 d


180-364 d


1-5 y


6-10 y


11 y and older




Limitations:Patients on warfarin may have decreased Protein C values. Patients should be off Warfarin therapy for two weeks for accurate measurement of Protein C.
Use:Aids in diagnosis of congenital deficiencies characterized by recurrent venous thrombosis. Acquired deficiencies associated with Protein C includes: oral anticoagulant therapy, liver disease, vitamin K deficiency. Malignancy, consumptive DIC, surgery, trauma, antibodies to Protein C and hepatic immaturity of the newborn.

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