Anti Ku Antibody - LG5393
| Sunquest Code: | LSMISC | ||
| Epic Code: | LAB4909 | Epic Name: | Send Outs Misc Test |
| Methodology: | Enzyme linked immunosorbent assay (ELISA). | ||
| Turnaround Time: | Specimens are sent to the reference laboratory Mon-Sat; results are reported within 16 days. | ||
| Compliance: | This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration. |
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Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 2.2 mL |
| Minimum\Peds Volume: | 1.2 mL Does not permit repeat analysis |
| Container: | Red or gold (gel) (Red (no gel)) |
| Causes for Rejection: | Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types. |
Processing and Shipping
| Specimen Processing: | Within one hour of collection centrifuge and aliquot 1 mL; 0.5 mL minimum. Store in refrigerator. |
| Shipping Instructions: | Ship at refrigerated temperature. |
| Stability: | 7 days room temperature; 14 days refrigerated; 60 days frozen. |
| Test Performed at or Referral Lab | Lab Sendouts (LabCorp via ARUP) |
| Referral Lab number: | 520030 |
Interpretive
| Reference Range: | Negative |
| Use: | Anti-Ku antibodies are found in about 20% of IIM; associated with overlap syndromes such as PM/SSc (most common), SLE/PM and other autoimmune disorders such as PM, SS, SSc, SLE, UCTD, MCTD, RA; common clinical features include arthralgias/arthritis, myositis, Raynaud's, esophageal dysmotility and ILD. |
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