Protein, Total, Serum/Plasma

Sunquest Code:TP  
Epic Code:LAB118Epic Name:Protein Total
Synonyms:TP; Total Protein; Tprot
Methodology:Bichromatic rate
Turnaround Time:Performed and reported 24 hours/day.

Collection Instructions

Optimal Volume:2.5 mL
Minimum\Peds Volume:0.6 mL
Container:Green (lithium heparin, gel) (Green (lithium heparin) on ICE, Red (no gel), Red or gold (gel))

Processing and Shipping

Specimen Processing:Centrifuge and aliquot 1.25 mL, 0.2 mL minimum. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Stability:Stability: Room temperature - 8 hours; refrigerated - 3 days; frozen - 6 months.
Test Performed at or Referral Lab Chemistry  (University of Minnesota Health Maple Grove Clinics, Fairview Range - FRMC, UMMC-East Bank, Oxboro Bloom, Fairview Lakes - FLMC, Fairview Ridges - FRH, Fairview Northland - FNMC, Fairview Southdale - FSH, UMMC/UMMCH-West Bank, M Health Clinic and Surgery Center, Grand Itasca GICH)


Reference Range:
Age Plasma, g/dL
0-3 y 5.5-7.0
4-9 y 6.5-8.4
10 y and older 6.8-8.8
GICH: All ages 6.4-8.9 g/dL
Reference range is on ambulatory patients in sitting position. Patients in recumbent position may have lower values by approximatley 6%. Serum specimens will be decreased by approximately 0.2-0.4 g/dL due to lack of fibrinogen.
Use:Albumin is the major serum protein, accounting for roughly half the total protein in most individuals. Excessive loss from the kidneys, GI tract, or skin such as with burns as well as decreased protein synthesis from malnutrition or liver disease can cause low serum albumin and to a lesser extent low total protein. Elevated albumin and total protein can be seen with dehydration. Elevated total protein with normal albumin suggests other serum proteins are elevated, seen most frequently in those with multiple myeloma.

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