Protein S Antigen, Total
| Abbrev Code: | ARMISC | ||
| Order Code: | LAB4909 | Order Name: | Sendout Misc Test |
| Order Instructions: | Do not order if individual has been on warfarin therapy in the previous 2-4 weeks. | ||
| Methodology: | Microlatex Particle - Mediated Immunoassay | ||
| CPT Codes: | 85305 x1, 85305 x1 | ||
| Turnaround Time: | Specimen sent to reference laboratory Mon-Fri; results reported within 3 days. | ||
| Compliance: | This test uses an in vitro diagnostic (IVD) that has been cleared or approved by the FDA. |
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| Associated Links: | Specimen Collection and Processing for Coagulation Specimens |
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Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | Three 2.7 mL (in 3 mL tube) - fill to fill line on the tube |
| Minimum\Peds Volume: | Two 2.7 mL (in 3 mL tube) - fill to fill line on the tube |
| Container: | Blue Na Citrate, 3.2% - fill to fill line on tube |
| Collection Instructions: | Patient should be off warfarin for at least 2 weeks before drawing sample. |
| Causes for Rejection: | Overfilled or underfilled tubes. Specimen other than citrated plasma. Clotted or hemolyzed specimens. Refrigerated specimens. |
Processing and Shipping
| Specimen Processing: | See link to Specimen Collection and Processing of Coagulation Specimens for platelet-poor plasma. Transfer 1.5 mL, minimum of 1 mL, platelet-poor plasma to an ARUP Standard Transport tube. Store frozen. |
| Shipping Instructions: | Ship frozen. |
| Stability: | 4 hours room temperature; 3 months frozen at -20°C; 6 months frozen at -70°C |
| Test Performed at or Referral Lab | Lab Sendouts (ARUP) |
| Referral Lab number: | 0030112 |
Interpretive
| Reference Range: |
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| Limitations: | Patients on warfarin may have decreased protein S values. Patients should be off warfarin therapy for two weeks for accurate measurement of protein S. | |||||||||||||||||||||||||||
| Use: | Not recommended for detecting protein S deficiency; preferred test is Protein S Free, Antigen (LAB492). Use to subtype deficiency in known protein S-deficient individuals in combination with Protein S Free, Antigen, or Protein S, Functional (Miscellaneous to ARUP test ID 0030114). |
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