Human Immunodeficiency Virus Type 1 (HIV-1) Trofile Co-Receptor Tropism

Abbrev Code:TROTRIP   
Order Code:LAB6664Order Name:Trofile Co-Receptor Tropism
Methodology:Recombinant virus, single replication
CPT Codes: 87999 x1, 87999 x1
Turnaround Time:Specimens are sent to reference laboratory Mon-Fri; results are reported within 16-23 days.
Special Instructions:Provide the patient's HIV 1 Viral Load.
Procedure should be used for patients with documented HIV-1 infection and viral loads greater than 1000 copies/mL.

Collection Instructions

Optimal Volume:6.2 mL
Container:Purple (EDTA)
Causes for Rejection:Thawed specimens.

Processing and Shipping

Specimen Processing:Within 6 hours of collection, centrifuge and aliquot 3 mL plasma. Freeze immediately.
Shipping Instructions:Ship on dry ice. CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Stability:2 weeks frozen at -20.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:3001246


Reference Range:By report.
For patients with HIV-1 viral loads ≥ 1000 copies/mL.
The US Department of Health and Human Services (DHHS) and the Infectious Diseases Society of America (IDSA) guidelines recommend that a coreceptor tropism test be performed whenever the use of CCR5 inhibitor is being considered. Coreceptor tropism testing might also be considered for patients who exhibit virologic failure on a CCR5 inhibitor.

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