Alpha-1-Antitrypsin Proteotype S/Z, Serum
Abbrev Code: | MMMISC | ||
Order Code: | LAB4909 | Order Name: | Send Outs Misc Test |
Synonyms: | Alpha 1 Antitrypsin Deficiency | ||
Methodology: | Liquid chromatography-Tandem mass spectrometry; Nephelometry; Isoelectric focusing | ||
CPT Codes: | 82103 x1, 82454 x1, 82104 x1 | ||
Test Includes: | A1AT proteotype s/Z, LC-MS/MS; Alpha-1-Antitrypsin serum with reflex to Alpha-1-Antitrypsin phenotyping. | ||
Turnaround Time: | Specimens are sent to reference laboratory Mon-Fri; results are reported within 7-14 days. |
Collection Instructions
Specimen: | Blood |
Optimal Volume: | 2.5 mL |
Minimum\Peds Volume: | 1.2 mL |
Container: | Red (no gel) Alternate Containers: Red or gold (gel) |
Causes for Rejection: | Grossly lipemic specimens. |
Processing and Shipping
Specimen Processing: | Centrifuge and aliquot 1.25 mL, 0.5 mL minimum. Store in refrigerator. |
Shipping Instructions: | Ship at refrigerated temperature. |
Stability: | Samples are stable for 28 days at room temperature, refrigerated or frozen. |
Test Performed at or Referral Lab | Lab Sendouts (Mayo Medical Laboratories) |
Referral Lab number: | A1ALC |
Interpretive
Reference Range: | Alpha-1-Antitrypsin: 100-190 mg/dL
Alpha-1-Antitrypsin Proteotype: Negative for S and Z phenotype (Non S Non Z) |
Use: | Determining the specific proteotype for prognosis and genetic counseling for patients with alpha-1-antitrypsin deficiency. |
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