Abbrev Code:PALPDN   
Order Code:LAB1203Order Name:Paliperidone
Order Instructions:This test detects paliperidone (9-hydroxyrisperidone) only. For risperidone (parent) AND paliperidone (9-hydroxyrisperidone, metabolite) order Risperidone and Metabolite.
Synonyms:9-hydroxyrisperidone; Invega
Methodology:Quantitative Liquid chromatography/Tandem mass spectrometry (LC/MS/MS)
CPT Codes: 80342 x1, 80342 x1
Turnaround Time:Specimens are sent to the reference laboratory Sun-Sat; testing is performed Wed, Sat and results are reported in 1-5 days.

ARUP Laboratory Developed Test (LDT): For tests developed and validated by ARUP (previously referred to as Compliance Statement B, C or D). This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Collection Instructions

Optimal Volume:2 mL
Minimum\Peds Volume:1.2 mL
Container:Red (no gel)
Alternate Containers: Purple (EDTA)
Collection Instructions:Pre-dose (trough) draw - at steady state concentration.

Processing and Shipping

Specimen Processing:Centrifuge and separate from cells ASAP or within 2 hours of collection. Aliquot 1 mL, 0.5 mL minimum, serum or plasma. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Stability:2 weeks at room temperature or refrigerated; 2 months frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:2007949


Critical Range:Toxic level: >120 ng/mL
Therapeutic Range:Paliperidone (9-hydroxyrisperidone): 20-60 ng/mL   The therapeutic range is based on serum pre-dose (trough) draw at steady state concentration. Adverse effects to paliperidone therapy may include headache, nausea, dizziness, tachycardia, orthostatic hypotension and dyskinesia.
Use:Optimize drug therapy and monitor patient adherence.

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