Alpha Defensin, Lateral Flow Assay, Synovial Fluid
Abbrev Code: | ALDEF | ||
Order Code: | LAB6665 | Order Name: | Alpha Defensin LFA Synovial Fluid |
Synonyms: | Synovasure; Periprosthetic Joint Infection (PJI) | ||
Methodology: | Lateral Flow Assay (LFA) | ||
CPT Codes: | 83518 x1, 83518 x1 | ||
Test Includes: | Alpha Definsin, CRP and hemoglobin on synovial fluid | ||
Turnaround Time: | Specimens are sent to the reference laboratory daily; testing is performed Mon, Fri, Sun and results are reported within 1 day. | ||
Special Instructions: | This test should only be used for patients with total joint prothesis. |
Collection Instructions
Specimen: | Synovial Fluid |
Optimal Volume: | 1 mL |
Minimum\Peds Volume: | 0.1 mL |
Container: | Plastic leakproof container, sterile Alternate Containers: Red (no gel) |
Collection Instructions: | Specimen source and type of joint are required. If not obtained from a prosthetic joint, testing will be cancelled. |
Causes for Rejection: | If not obtained from a prosthetic joint, testing will be cancelled. |
Processing and Shipping
Specimen Processing: | Do not process. Transport specimen in the original collection container. Indicate specific collection site on collection container. Separate specimens must be submitted when multiple tests are ordered. Store in refrigerator. |
Shipping Instructions: | Ship at refrigerated temperature. |
Stability: | 7 days refrigerated. |
Test Performed at or Referral Lab | Lab Sendouts (Mayo Medical Laboratories) |
Referral Lab number: | ALDEF |
Interpretive
Reference Range: |
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Limitations: |
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Use: | Alpha defensin in synovial fluid detected, suggesting presence of prothetic joint infection. Additional microbiolgic studies (e.g., culture, molecular detection) are recommended.
Detection of alpha defensins 1-3, human host response proteins, in synovial fluid of adults with a total joint replacement who are being evaluated for revision surgery. This test is not intenteded to be used to determine timing for reimplantation in 2-stage procedures. |
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