PRA, Interfering Substance Screen

Abbrev Code:PRAIS   
Order Code:LAB6459Order Name:PRA, Interfering Substance SCR
Order Instructions:If this test is being added on, comment ADD-ON in the Comment field when placing a normal order in Epic.
Methodology:Luminex solid phase assay.
Test Includes:Expanded PRA
Turnaround Time:Results are reported within 7 days.

Collection Instructions

Optimal Volume:14 mL
Minimum\Peds Volume:3 mL
Container:Red (no gel)
Alternate Containers: Red (gel)
Collection Instructions:Collect specimen prior to dialysis. Do not collect specimen if patient has received IVIG, OKT3 or Campath recently; these drugs may cause false positive results. Inform lab if patient has received anti-thymoglobulin. Lab must remove serum prior to testing.
Causes for Rejection:Gross hemolysis; immunosuppression drug interference.
Contraindications:Serum will not clot if collected during or immediately after dialysis.

Processing and Shipping

Specimen Processing:Do not process (preferred). If processed, remove serum. Store at room temperature.
Shipping Instructions:Ship at room temperature; protect from temperature extremes.
Stability:Store at room temperature (preferred); refrigerated or frozen.
Test Performed at or Referral Lab Immunology  (UMMC East Bank)


Use:Expanded detection of HLA Class I or Class II antibodies in patient serum. High levels of HLA antibody may result in difficulty finding a compatible organ donor.

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