PRA, Interfering Substance Screen
| Abbrev Code: | PRAIS | ||
| Order Code: | LAB6459 | Order Name: | PRA, Interfering Substance SCR |
| Order Instructions: | If this test is being added on, comment ADD-ON in the Comment field when placing a normal order in Epic. | ||
| Methodology: | Luminex solid phase assay. | ||
| Test Includes: | Expanded PRA | ||
| Turnaround Time: | Results are reported within 7 days. | ||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 14 mL |
| Minimum\Peds Volume: | 3 mL |
| Container: | Red (no gel) Alternate Containers: Red (gel) |
| Collection Instructions: | Collect specimen prior to dialysis. Do not collect specimen if patient has received IVIG, OKT3 or Campath recently; these drugs may cause false positive results. Inform lab if patient has received anti-thymoglobulin. Lab must remove serum prior to testing. |
| Causes for Rejection: | Gross hemolysis; immunosuppression drug interference. |
| Contraindications: | Serum will not clot if collected during or immediately after dialysis. |
Processing and Shipping
| Specimen Processing: | Do not process (preferred). If processed, remove serum. Store at room temperature. |
| Shipping Instructions: | Ship at room temperature; protect from temperature extremes. |
| Stability: | Store at room temperature (preferred); refrigerated or frozen. |
| Test Performed at or Referral Lab | Immunology (UMMC East Bank) |
Interpretive
| Use: | Expanded detection of HLA Class I or Class II antibodies in patient serum. High levels of HLA antibody may result in difficulty finding a compatible organ donor. |
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