PRA, Donor Specific Antibody

Abbrev Code:PRADSA   
Order Code:LAB6445Order Name:PRA, Donor Specific Aby
Order Instructions:If this test is being added on, comment ADD-ON in the Comment field when placing a normal order in Epic. Immunology will receive the printout directly. All other lab areas should discard the Immunology ADD-ON printout.
Synonyms:HLA Class I/II Antibody; PRA (Panel Reactive Antibody); WBC Antibody; White Cell Antibody; Antileukocyte Antibody; IMM3
Methodology:Luminex solid phase assay
CPT Codes: 86832 x1, 86832 x1, 86833 x1, 86833 x1
Turnaround Time:Results are reported within 7 days.
Special Instructions:If testing is requested on a patient that has received a transplant at an outside institution, the following information must be provided: Recipient HLA type, Donor HLA type.

Collection Instructions

Optimal Volume:14 mL
Minimum\Peds Volume:3 mL
Container:Red (no gel)
Alternate Containers: Red (gel)
Collection Instructions:Collect specimen prior to dialysis. Do not collect specimen if patient has received IVIG, OKT3 or Campath recently; these drugs may interfere with testing.
Causes for Rejection:Gross hemolysis; immunosuppression drug interference.
Contraindications:Serum will not clot if collected during or immediately after dialysis.

Processing and Shipping

Specimen Processing:Do not process (preferred). If processed, remove serum. Store at room temperature.
Shipping Instructions:Ship at room temperature. Protect from temperature extremes.
Stability:Store at room temperature (preferred), refrigerated or frozen.
Test Performed at or Referral Lab Immunology  (UMMC East Bank)


Use:Detection of HLA Class I and/or Class II antibodies in patient serum. High levels of HLA antibody may result in difficulty in finding a compatible organ or marrow donor.

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