Epidermal Nerve Fiber
| Abbrev Code: | ENF | ||
| Order Code: | LAB6605 | Order Name: | Epidermal Nerve Fiber Density |
| Order Instructions: | Only one Epidermal Nerve Fiber order is required for multiple samples. Order one ENF and transport all biopsies together. | ||
| Synonyms: | ENF; Skin Biopsy for Nerve Density; Confocal Microscopy | ||
| Methodology: | Immunofluorescent localization of nerve/tissue antigens in skin sections, confocal microscopy, tracing and quantification of epidermal nerve fibers, report of nerve fiber density, general innervation morphology | ||
| CPT Codes: | 88314 x1, 88305 x1, 88346 x1, 88348 x1, 88356 x1, 88350 x5 | ||
| Turnaround Time: | Specimens are sent to reference laboratory Mon-Thur; results are reported within 15 days | ||
| Special Instructions: | STAT processing required. Sample must be in Zamboni fixative within 4 hours and arrive in performing lab within 24 hours. Place tissues directly into Zamboni fixative (available from Kennedy Lab 612-625-1431) immediately upon excision and send to UMMC-East Core Lab for delivery to the Kennedy Laboratory, J-119 Diehl Hall. | ||
Collection Instructions
| Specimen: | Tissue-Skin Biopsy |
| Optimal Volume: | 3 mm |
| Container: | Zamboni Fixative Vial |
| Collection Instructions: | Place tissues directly into Zamboni fixative-containing vial immediately upon excision. Place vial with specimen in stryrofoam container with an ice pack. |
| Causes for Rejection: | Damaged tissue, frozen tissue, tissue not in fixative. |
Processing and Shipping
| Specimen Processing: | STAT processing required. See Special Instructions.
UMMC East Bank Core: Check in sample and call Kennedy for pick up ASAP. Log sample on the Pass-Thru Log and store refrigerated in the Pass-Thru bucket. Keep refrigerated; do not freeze. |
| Shipping Instructions: | Ship at refrigerated temperatures. Do not freeze. |
| Test Performed at or Referral Lab | Lab Sendouts (Kennedy Lab, J-119 Diehl Hall) |
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