Hepatitis C Screen with Reflex to HCV RNA Quantitation and HCV Genotype
| Sunquest Code: | HCVSR | ||
| Epic Code: | LAB6672 | Epic Name: | Hepatitis C Screen Reflex to HCV RNA Quant and Genotype |
| Methodology: | Chemiluminescent immunoassay; molecular | ||
| Test Includes: | Hepatitis C Antibody Screen with reflex to Hepatitis C RNA, Quantitation, Real-Time PCR (HCQNT) and Hepatitis C Virus High Resolution Genotyping (HEPCHI) if positive with greater than a log of 3.6. | ||
| Turnaround Time: | Performed Mon-Fri; results are reported within 4 days for in house testing. An additional 8-10 days is required for specimens sent to reference lab for HCV genotyping | ||
| Associated Links: | |||
Collection Instructions
| Specimen: | Blood |
| Optimal Volume: | 8 mL |
| Minimum\Peds Volume: | 3.8 mL |
| Container: | Red or gold (gel) (Purple (EDTA), Red (no gel)) |
| Collection Instructions: | Serum is preferred. EDTA plasma is also acceptable. Serum is the only acceptable sample for neonates. |
| Causes for Rejection: | See individual test codes (HCVAB, HCQNT and HEPCHI). A green (lithium heparin, gel tube is unacceptable for screening.) For a reactive HCV antibody screen, the sample must be frozen within 72 hours of collection to run the Hepatitis C RNA, Quantitation and Hepatitis C Genotyping. |
Processing and Shipping
| Specimen Processing: | Centrifuge and leave sample in serum separator tube. If necessary, aliquot 4 mL, 1.8 mL minimum. Store in refrigerator up to 3 days. Freeze samples if transport time is greater than 3 days. |
| Shipping Instructions: | Ship at refrigerated or frozen temperature. |
| Stability: | Stability: 72 hours refrigerated; 4 months frozen. |
| Test Performed at or Referral Lab | Specialty Core (UMMC-East Bank) |
Interpretive
| Reference Range: | Nonreactive. Assay performance characteristics have not been established for newborns, infants or children. |
| Use: | Used for patients born between 1945-1965 following the CDC recommendations. Can also be used for any patient for which it is clinically recommended. |
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