Urticaria Induced Basophil Activation


Abbrev Code:UIBASA   
Order Code:LAB6817Order Name:Urticaria Basophil Activation
Methodology:Semi-quantitative flow cytometry
CPT Codes: 88184 x1, 88185 x2
Turnaround Time:Specimens are sent to reference laboratory Mon-Sat; results are reported within 7-10 days.
Compliance:

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the U.S. Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.



Collection Instructions

Specimen:Blood
Optimal Volume:2 mL
Minimum\Peds Volume:1.2 mL
Container:Red (no gel)
Causes for Rejection:Specimens other than serum. Contaminated, grossly hemolyzed or lipemic specimens.


Processing and Shipping

Specimen Processing:Centrifuge and aliquot 1 mL, 0.5 mL minimum within 2 hours of collection. Store frozen.
Shipping Instructions:Ship at frozen temperature. CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Stability:After separation from cells: 30 minutes at room temperature; unacceptable refrigerated; 1 year frozen.
Test Performed at or Referral Lab Lab Sendouts  (ARUP)
Referral Lab number:2005416


Interpretive

Reference Range:

27 percent or less

Negative – No basophil activation detected.

28-38 percent

Indeterminate – Borderline basophil activation detected.

39 percent or greater

Positive – Basophil activation detected.

 

 

Use:Determine whether CD203c is upregulated in suspected chronic urticaria if urticaria is felt to be due to autoimmune antibodies to the basophil IgE receptor or to IgE.


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