Dementia Auto-Immune Evaluation, CSF - LG6465


Sunquest Code:MMMISC  
Epic Code:LAB4909Epic Name:Send Out Misc Tests
Methodology:Indirect immunofluorescence assay, Radioimmunoassay, Western blot, Cell binding assay
Turnaround Time:Specimens are sent to reference laboratory Mon-Fri; results are reported within 3-10 days.


Collection Instructions

Specimen:CSF
Optimal Volume:4 mL
Minimum\Peds Volume:2 mL
Container:Sterile tube
Causes for Rejection:Grossly hemolyzed or lipemic specimens


Processing and Shipping

Specimen Processing:Do not process. Store in refrigerator.
Shipping Instructions:Ship at refrigerated temperature.
Stability:Stability: 72 hours at room temperature; 28 days refrigerated (preferred) or frozen.
Test Performed at or Referral Lab Lab Sendouts  (Mayo Medical Laboratories)
Referral Lab number:DMC2


Interpretive

Reference Range:

Anti-neuronal Nuclear Ab, Type 1 (ANNA-1), CSF

<1:2

Anti-neuronal Nuclear Ab, Type 2 (ANNA-2), CSF

<1:2

Anti-neuronal Nuclear Ab, Type 3 (ANNA-3), CSF

<1:2

Purkinje Cell Cytoplasmic Ab, Type 1 (PCA-1), CSF

<1:2

Purkinje Cell Cytoplasmic Ab, Type 2 (PCA-2), CSF

<1:2

Purkinje Cell Cytoplasmic Ab, Type Tr (PCA-Tr), CSF

<1:2

Amphiphysian Ab, CSF

<1:2

CRMP-5-IgG Ab, CSF

<1:2

Paraneoplastic Western Blot, CSF

Negative

CRMP-5-IgG Western Blot, CSF

Negative

Amphiphysin Western Blot, CSF

Negative

Glutamic Acid Decarboxylase-65 (GAD65) CSF

≤ 0.02 nmol/L

Neuronal Voltage-Gated Postassium Channel-Complex Autoantibody, Spinal Fluid

≤ 0.02 nmol/L

N-Methyl-D-aspartate receptor (NMDA-R), CSF,    CBA

Negative

N-Methyl-D-aspartate receptor (NMDA-R), CSF,    IFA

<1:2

2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4yl) propanoic acid receptor (AMPA-R), CSF    CBA

Negative

2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4yl) propanoic acid receptor (AMPA-R), CSF    IFA

<1:2

Gamma-Amino Butyric Acid – Type B Receptor (GABA-B-R), CSF    CBA

Negative

Gamma-Amino Butyric Acid – Type B Receptor (GABA-B-R), CSF    IFA

<1:2

Anti-Glial/Neuronal Nuclear Ab, Type 1 (AGNA-1), CSF

<1:2

NMO/AQP4-IgG, CSF

Negative

 LG11-IgG CBA, CSF: Negative

 CASPR2-IgG, CSF: Negative

 

Use:Investigating new onset dementia and cognitive impairment.


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