Hereditary Cancer Gyn Expanded


Abbrev Code:GYNEXP   
Order Code:LAB7082Order Name:Hereditary Cancer Gyn Expanded
Synonyms:Ovarian Cancer Syndrome; Gynecological I Cancer; NGS; Next Generation Sequencing
Methodology:Next generation sequencing
CPT Codes: 81297 x1, 81298 x1, 81300 x1, 81479 x1, 81317 x1, 81319 x1, 81479 x1, 81479 x1, 81479 x1, 81406 x1, 81406 x1, 81406 x1, 81479 x1, 81479 x1, 81479 x1, 81479 x1, 81479 x1, 81408 x1, 81408 x1, G0452 x1, 81321 x1, 81404 x1, 81405 x1, 81162 x1, 81405 x1, 81479 x1, 81323 x1, 81403 x1, 81292 x1, 81294 x1, 81295 x1
Turnaround Time:Testing is performed Mon-Fri; results are reported within 28-42 days.
Special Instructions:Gene(s) or the name of the panel should be indicated in the comment section of EPIC order.
A signed informed consent in the patient's medical record is required; the consent should not be sent to the laboratory. The link to the Genetic Testing Consent Form is provided as a convenience for the providers and genetic counselors.
Bone Marrow Transplant Patients: If a patient is the recipient of an allogeneic transplant, this test must be done on a pre-transplant sample Contact the Molecular Diagnostics lab to see if a pre-transplant sample is available.
Associated Links:

NGS Genetic Testing Consent Form



Collection Instructions

Specimen:Blood
Optimal Volume:10 mL
Minimum\Peds Volume:3 mL
Container:Yellow (ACD, Solution A) tube available from laboratory
Alternate Containers: Purple (EDTA)
Causes for Rejection:Frozen or clotted specimen, incorrect anticoagulant, specimen more than 5 days old. Sample collected from bone marrow transplant recipient. Samples tested in hematology using automated instrumentation not accepted. DNA extracted at non-CLIA certified (or equivalent) lab.


Processing and Shipping

Specimen Processing:Do not process. Store at room temperature.
Shipping Instructions:Ship at room temperature.
Stability:5 days at room temperature.
Test Performed at or Referral Lab Molecular Diagnostics  (UMMC-East Bank)


Interpretive

Reference Range:By report.
Use:This testing is used to identify inherited risks for cancers in patients with a clinical presentation and/or family history strongly suggestive of an hereditary cancer predisposition. This testing is typically performed through a genetic counselor and many insurance companies require documentation of genetic counseling in order for the testing to be covered.


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